Affiliation: Laboratory of Chemical Physics, NIDDK,
NIH
Research: Development and application of improved NMR methods
for the study of macromolecular structure and dynamics including
methods which provide additional structural constraints for obtaining higher
definition of macromolecular structure.
methods and procedures for facilitating the resonance assignment process.
methods for a better characterization of internal and overall macromolecular
dynamics.
methods for extending the molecular weight limit of systems that can be
studied.
Equipment: The group is equipped with a 600 MHz Bruker DMX NMR spectrometer
capable of triple resonance and pulsed field gradient experiments, and
shares a 900MHz, 800MHz, a 750 MHz and a 500 MHz spectrometer with the
groups of
G.M.
Clore,
R.
Tycko,
D.A.
Torchia and N. Tjandra.