Solution structure of the 40 kDa Enzyme I-HPr Complex of the E. coli Phosphotransferase System

 

 

Diagram of the Glucose Arm of the PTS pathway

pts pathway

EI-HPr complex

e1_hpr complex

Phosphoryl transition state

transition state

Garrett, D.S., Seok, Y.J., Liao, D.I., Peterkofsky, A., Gronenborn, A.M. & Clore, G.M. (1997) Solution structure of the 30 kDa N-terminal domain of Enzyme I of the Escherichia coli phosphoenolpyruvate:sugar phosphotransferase system by multidimensional NMR. Biochemistry 36, 2517-2530. pubmed PDF

Garrett, D.S., Seok, Y.-J., Peterkofsky, A., Gronenborn, A.M. & Clore, G.M. (1999) Solution structure of the 40,000 Mr phosphoryl transfer complex between Enzyme I and HPr. Nature Struct. Biol. 6, 166-173. pubmed PDF

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