Dr. Tobias Ulmer

National Institutes of Health
Laboratory of Chemical Physics, NIDDK
Building 5, Room B1-31
5 Center Drive
Bethesda, MD 20892-0520

Tel: 301 594-8301
Fax: 301 496-0825
E-mail: tobias.ulmer@nih.gov

RESEARCH INTERESTS

Structural Biology. Structure-function relationships of proteins. Molecular Evolution. NMR spectroscopy.

EDUCATION

D. Phil. (Ph.D.) in Biophysics (2002), University of Oxford, England
Diplom (M.Sc.) in Biochemistry (1998), University of Zurich, Switzerland

PROFESSIONAL EXPERIENCE

Post-Doctoral Fellow
National Institutes of Health, Bethesda, Maryland, USA , 2002-present

Teaching
Merton College, University of Oxford, England, 2000-2001

AWARDS

Human Frontier Science Program (HFSP) Long-Term Fellowship, 2002 - present

Student Travel Stipend, 42nd ENC, Orlando, 2001

Special Research Studentship from the Biotechnology and Biological

Sciences Research Council (BBSRC), UK, 1999-2001
Postgraduate Studentship from the German Academic Exchange Service (DAAD), 1998-1999

PUBLICATIONS

Publications from the Bax Group

Ulmer, T. S., Ramirez, B. E., Delaglio, F., and Bax, A., Evaluation of backbone proton positions and dynamics in a small protein by liquid crystal NMR spectroscopy, J. Am. Chem. Soc. 125 (2003) 9179-9191.

Ulmer, T. S., Soelaiman, S., Li, S. P., Klee, C. B., Tang, W. J., and Bax, A., Calcium dependence of the interaction between calmodulin and anthrax edema factor, J. Biol. Chem. 278 (2003) 29261-29266.

Other publications

Ulmer, T. S., Campbell, I. D., and Boyd, J., Amide Proton Relaxation Measurements in a Highly Deuterated Protein, J. Magn. Reson. in press

Ulmer, T. S., Calderwood, D. A., Ginsberg, M. H., and Campbell, L. D., Domain-specific interactions of Talin with the membrane- proximal region of the integrin beta 3 subunit, Biochemistry 42 (2003) 8307-8312.

Garcia-Alvarez, B., de Pereda, J. M., Calderwood, D. A., Ulmer, T. S., Critchley, D., Campbell, I. D., Ginsberg, M. H., and Liddington, R. C., Structural determinants of integrin recognition by Talin, Mol. Cell 11 (2003) 49-58.

Ulmer, T. S., Werner, J. M., and Campbell, I. D., SH3-SH2 domain orientation in Src kinases: NMR studies of Fyn, Structure 10 (2002) 901-911.

Ulmer, T. S., Campbell, I. D., and Boyd, J., The effects of dissolved oxygen upon amide proton relaxation and chemical shift in a perdeuterated protein, J. Magn. Reson. 157 (2002) 181-189.

Ulmer, T. S., Yaspan, B., Ginsberg, M. H., and Campbell, I. D., NMR analysis of structure and dynamics of the cytosolic tails of integrin alpha IIb beta 3 in aqueous solution, Biochemistry 40 (2001) 7498-7508.

Ginsberg, M. H., Yaspan, B., Forsyth, J., Ulmer, T. S., Campbell, I. D., and Slepak, M., A membrane-distal segment of the integrin alpha(IIb) cytoplasmic domain regulates integrin activation, J. Biol. Chem. 276 (2001) 22514-22521.

Arold, S. T., Ulmer, T. S., Mulhern, T. D., Werner, J. M., Ladbury, J. E., Campbell, I. D., and Noble, M. E. M., The role of the Src homology 3-Src homology 2 interface in the regulation of Src kinases, J. Biol. Chem. 276 (2001) 17199-17205.