Dr. Jerome Boisbouvier

National Institutes of Health
Building 5, Room B1-27
9000 Rockville Pike
Bethesda, MD 20892-0520

Tel.: 301-496-7098
Fax: 301-496-0825

E-mail: jeromeb@speck.niddk.nih.gov


Biophysical NMR : Methods & Applications. Structural & Dynamical Studies of Proteins and Nucleic Acids


Ph.D. in Physics
Joseph Fourier University, Grenoble - France - 2000

Specialized Master's in Chemistry ("Magistere")
Ecole Normale Superieure, Paris - France - 1997

Diploma of Advanced Studies in Molecular Biophysics ("DEA")
Pierre & Marie Curie University, Paris - France - 1996

Master's degree in Chemistry
Ecole Normale Superieure, Paris - France - 1995

Competitive Examination for Admission at Ecole Normale Superieure
Specialization : Biology, Paris - 1994


Post-Doctoral Fellow, Biophysical NMR Section, Supervisor: Dr. A. Bax
National Institutes of Health, Bethesda, MD, USA , 2001-present

Military Scientist, Biophysics Laboratory, Supervisor: Dr. J.C. Debouzy
Research Center of Army Health Service, La Tronche - France, 2000-2001

Research Fellow, NMR Laboratory, Supervisor: Dr. D. Marion
Institute of Structural Biology, Grenoble - France, 1996-2000

Research Fellow, NMR Laboratory, Supervisor: Dr. M. Delepierre
Pasteur Institute, Paris - France, 1996


Human Frontier Science Program Fellowship, 2001- present.
Young Researcher Prize of The French Biophysical Society - 2001.
French Ministry of Research Fellowship, 1998-2000.
French Government Fellow (grant from Ecole Normale Superieure), 1994-1998.


Publications from the Bax Group

Previous  Publications:

Brutscher B., Boisbouvier J., Kupce E., Tisne C., Dardel F., Marion D. & Simorre J.-P. "Base-type-selective high resolution 13C edited NOESY for sequential assignment of large RNA" J. Biomol. NMR, 19, pp 141-151 (2001).

Boisbouvier J., Brutscher B., Pardi A., Marion D & Simorre J.-P. "NMR determination of sugar puckers in nucleic acids from CSA-dipolar cross-correlated relaxation" J. Am. Chem. Soc., 122, pp 6779-6780 (2000).

Boisbouvier J., Blackledge M., Sollier A. & Marion, D. "Simultaneous determination of disulphide bridge topology and three-dimensional structure using ambiguous intersulphur distance restraints: Possibilities and limitations" J. Biomol. NMR., 16, pp 197-208 (2000).

Delepierre M., Prochnicka-Chalufour A., Boisbouvier J. & Possani, L.D. "Pi7, an Orphan Peptide from the Scorpion Pandinus Imperator : A 1H NMR Analysis Using a Nano-NMR Probe" Biochemistry, 38, pp 16756-16765 (1999).

Boisbouvier J., Gans P., Blackledge M., Brutscher B. & Marion, D. "Long-revange structural information in NMR studies of paramagnetic molecules from electron spin - nuclear spin cross-correlated relaxation" J. Am. Chem. Soc., 121, pp 7700-7701 (1999).

Boisbouvier J., Brutscher B,. Simorre J.-P & Marion D. "13C spin relaxation measurements in RNA : Sensitivity and resolution improvement using spin-state selective correlation experiments" J. Biomol. NMR., 14, pp 241-252 (1999).

Brutscher B., Boisbouvier J., Pardi A., Marion D. & Simorre J.-P. "Improved Sensitivity & Resolution in 1H-13C NMR Experiments of RNA" J. Am. Chem. Soc., 120, pp 11845-11851 (1998).

Boisbouvier J., Albrand J.-P., Blackledge M., Jaquinod M., Schweitz H., Lazdunski M. & Marion D. "A Structural Homologue of Mammal Pancreatic Colipase in Black Mamba Venom Revealed by NMR Floating Disulphide Bridge Analysis" J. Mol. Biol., 283, pp 205-219 (1998).

Boisbouvier J., Prochnicka-Chalufour A., Nieto A.R., Torres J.A., Nanard N., Rodriguez M.H., Possani L.D. & Delepierre M. "Structural information on a cecropine-like synthetic peptide, Shiva-3 toxic to the development of Plasmodium Berghei" Eur. J. Biochem., 257, pp 263-273 (1998).

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