1. Clore, G.M. & Chance, E.M. (1977) A computer analysis of cyanide stimulated oxygen uptake in Chlorella protothecoides. FEBS Lett. 79, 353-356. PDF
2. Clore, G.M. & Shephard, E.P. (1978) Exact solution of the mass transfer equations of gel filtration chromatography by means of a formal inversion of the Laplace transform, and the derivation on an equation for the time spent by a molecule in the gel phase. J. Chromatogr. 152, 1-10. PDF 3. Clore, G.M. & Chance, E.M. (1978) The mechanism of the reaction of fully reduced membrane bound cytochrome oxidase with oxygen at 176 K. Biochem. J. 173, 799-810. pubmed PDF 4. Clore, G.M. & Chance, E.M. (1978) The kinetics of the reaction of ferricyanide pretreated mixed valence state membrane bound cytochrome oxidase with oxygen at 173 K. Biochem. J. 173, 811-820. pubmed PDF 5. Clore, E.M. & Chance, E.M. (1978) The kinetics and thermodynamics of the reaction of solid state fully reduced membrane bound cytochrome oxidase with carbon monoxide as studied by dual wavelength multichannel spectroscopy and flash photolysis. Biochem. J. 175, 709-725. pubmed PDF
6. Clore, E.M. & Chance, E.M. (1979) Low temperature kinetics of the reaction of fully reduced membrane bound cytochrome oxidase with oxygen in the Soret, a and near infrared regions. Biochem. J. 177, 613-621. pubmed PDF 7. Clore, G.M. (1979) The mechanism of the fully reduced and mixed valence state membrane bound cytochrome oxidase-oxygen reactions in the 173-176 K temperature range. In Cytochrome Oxidase (King, T.E., Orii, Y., Chance, B. and Okunuki, K., eds.) pp. 341-352, North Holland Elsevier, Amsterdam. 8. Denis, M. & Clore, G.M. (1979) A temperature induced absorption band centered in the region of 666 nm related to the configuration of the active site in frozen cytochrome oxidase. Biochim. Biophys. Acta 545, 483-495. pubmed PDF 9. Karlsson, B., Andreasson, L.E., Aasa, R., Malmstrom, B.G. & Clore, G.M. (1979) Studies of the reaction of cytochrome c oxidase with oxygen at low temperature. Acta Chem. Scand. Ser. B 33, 615-618.
10. Clore, G.M., Andreasson, L.E., Karlsson, B., Aasa, R. & Malstrom, B.G. (1980) Characterization of the low temperature intermediates of the reaction of fully reduced soluble cytochrome oxidase with oxygen by electron paramagnetic resonance and optical spectroscopy. Biochem. J. 185, 139-154. pubmed PDF 11. Clore, G.M., Andreasson, L.E., Karlsson, B., Aasa, R. & Malmstrom, B.G. (1980) Characterization of the intermediates in the reaction of mixed valence state soluble cytochrome oxidase with oxygen at low temperatures by optical and electron paramagnetic resonance spectroscopy. Biochem. J. 185, 155-167. pubmed PDF 12. Clore, G.M. (1980) Chracterization of the intermediates in the reaction of membrane bound mixed valence state cytochrome oxidase with oxygen at low temperatures by optical spectroscopy in the visible region. Biochem. J. 187, 617-622. pubmed PDF 13. Clore, G.M. (1980) The mechanism of reduction of dioxygen by fully reduced cytochrome oxidase: correlation of room and low temperature studies. Rev. Inorg. Chem. 2, 343-360. 14. Clore, G.M. & Chance, E.M. (1980) CO binding to mitochondrial mixed valence state cytochrome oxidase at low temperatures. Biochim. Biophys. Acta 590, 34-49. pubmed PDF 15. Campbell, J.R., Clark, R.J.H., Clore, G.M. & Lane, A.N. (1980) Characterization of the electronic properties and geometric environment of the iron atom in the 'myoglobin-hydrogen peroxide' complex by Soret-excited resonance Raman spectroscopy. Inorg. Chim. Acta 46, 77-84. PDF 16. Clore, G.M., Lane, A.N. & Hollaway, M.R. (1980) The kinetics of the reaction of aquo Fe(III) myoglobin with hydrogen peroxide at pH 8. Inorg. Chim. Acta 46, 139-146. PDF
17. Clore, G.M. (1981) A re-evaluation of the low temperature kinetics of the reaction of fully reduced mitochondrial cytochrome oxidase with carbon monoxide and the spectral characterization of species IC in the Soret and visible regions. Biochim. Biophys Acta 634, 129-139. pubmed PDF 18. Chance, E.M., Clore, G.M., Curtis, A.R. & Shephard, E.P. (1981) Numerical solution of the Hodgkin-Huxley equations in a moving coordinate system: simulation of nerve impulse transmission over long distances. J. Comp. Phys. 40, 318-326. 19. Clore, G.M. & Denis, M. (1981) Spectroscopic evidence for an oxygen bridge between the iron atom of cytochrome a3 and CuB in the Class C group of compounds formed in the reaction of mixed valence state cytochrome oxidase with oxygen. Inorg. Chim. Acta 55, L47-L49. PDF 20. Denis, N. & Clore, G.M. (1981) The reaction of mixed valence state cytochrome oxidase with oxygen in plant mitochondria: a study by low temperature flash photolysis and rapid wavelength scanning optical spectroscopy. Plant Physiol. 68, 229-235. PDF 21. Clore, G.M. (1981) The mechanism of the reaction of fully reduced cytochrome oxidase with oxygen at low temperatures: a kinetic study by electron paramagnetic resonance and optical spectroscopy. In Oxygen and Life, Royal Society of Chemistry Special Publications No. 39, pp. 189-198, The Royal Society of Chemistry, London. 22. Clore, G.M., Hollaway, M.R., Orengo, C., Peterson, J. & Wilson, M. (1981) The mechanism of the reactions of low spin ferric haem undecapeptide with hydrogen peroxide. Inorg. Chim. Acta 56, 143-148. PDF 23. Birdsall, B., Gronenborn, A.M., Clore, G.M., Roberts, G.C.K., Feeney, J. & Burgen, A.S.V. (1981) 13C-NMR evidence for three slowly interconverting conformations of the dihydrofolate reductase-NADP+-folate complex. Biochem. Biophys. Res. Commun. 101, 1139-1141. pubmed PDF 24. Gronenborn, A.M., Clore, G.M. & Davies, R.W. (1981) Modulation of specific binding of Lactobacillus casei dihydrofolate reductase to DNA by folinic acid. FEBS Lett. 133, 92-94. pubmed PDF 25. Clore, G.M., Roberts, G.C.K., Gronenborn, A.M., Birdsall, B & Feeney, J. (1981) Transfer of saturation NMR studies of protein-ligand complexes: the case of three site exchange. J. Magn. Reson. 45,151-161. PDF 26. Gronenborn, A.M., Clore, G.M., Blazy, B. & Baudras, A. (1981) Conformational selection of syn-cAMP upon binding to the cAMP receptor protein: a 1H-NMR study. FEBS Lett. 136, 160-164. pubmed PDF
27. Clore, G.M. & Gronenborn, A.M. (1982) Kinetic and structural studies on the intermediates formed in the reactions of 5'-adenosine monophosphate and 5'-guanosine monophosphate with cis-dichlorodiammineplatinum II using 1H and 195Pt magnetic resonance spectroscopy. J. Am. Chem. Soc. 104, 1369-1375. PDF 28. Clore, G.M., Gronenborn, A.M. & Davies, R.W. (1982) Theoretical aspects of specific and non-specific equilibrium binding of a protein to DNA as studied by the nitrocellulose filter binding assay: cooperative and non-cooperative binding to a one-dimensional lattice. J. Mol. Biol. 155, 447-466. pubmed PDF 29. Clore, G.M. & Gronenborn, A.M. (1982) Theory and applications of the transferred nuclear Overhauser effect to the study of the conformations of small ligands bound to proteins. J. Magn. Reson. 48, 402-417. PDF 30. Gronenborn, A.M. & Clore, G.M. (1982) Conformation of NAD+ bound to yeast and horse liver alcohol dehydrogenase in solution: the use of the proton-proton transferred nuclear Overhauser enhancement. J. Mol. Biol. 157, 155-160. pubmed PDF 31. Takahashi, M., Gronenborn, A.M., Clore, G.M., Blazy, B. & Baudras, B. (1982) DNA binding of cAMP receptor protein and its N-terminal core stabilizes the double helix and is modulated by cAMP. FEBS Lett. 139, 37-40. PDF 32. Gronenborn, A.M. & Clore, G.M. (1982) Proton nuclear magnetic resonance studies on cyclic nucleotide binding to the Escherichia coli adenosine 3',5'-phosphate receptor protein. Biochemistry 21, 4040-4048. pubmed PDF 33. Clore, G.M. & Gronenborn, A.M. (1982) A proton nuclear magnetic resonance study of the histidine residues of the Escherichia coli adenosine 3',5'-phosphate receptor protein: pH titration behaviour, deuterium exchange and partial assignments. Biochemistry 21, 4048-4053. pubmed PDF 34. Clore, G.M. & Gronenborn, A.M. (1982) Determination of the conformations of cyclic nucleotides bound to the N-terminal core of the cyclic AMP receptor protein of Escherichia coli by 1H-NMR. FEBS Lett. 145, 197-202. pubmed PDF 35. Clore, G.M., Gronenborn, A.M., Mitchinson, C. & Green, N.M. (1982) 1H-NMR studies on nucleotide binding to the sarcoplasmic reticulum Ca2+ATPase: determination of the conformations of bound nucleotides by the measurement of proton-proton transferred nuclear Overhauser enhancements. Eur. J. Biochem. 128, 113-117. pubmed PDF 36. Birdsall, B., Gronenborn, A.M., Hyde, E.I., Clore, G.M., Roberts, G.C.K., Feeney, J. & Burgen, A.S.V. (1982) 1H, 13C and 31P NMR studies of the dihydrofolate reductase-NADP+-folate complex: characterization of three coexisting conformational states. Biochemistry 21, 5831-5838. pubmed PDF
37. Clore, G.M. (1983) Computer analysis of transient kinetic data. In Computing in Biological Science (Geisow, M.J. & Barrett, A.N., eds.) pp. 313-348, Elsevier North-Holland, Amsterdam. 38. Unger, B., Clore, G.M., Gronenborn, A.M. & Hillen, W. (1983) Specific DNA binding of the cyclic AMP receptor protein with the lac operon stabilizes double stranded DNA in the presence of cAMP. EMBO J. 2, 289-293. pubmed PDF 39. Gronenborn, A.M., Clore, G.M. & Gronenborn, B. (1983) Protection against nuclease cleavage of pBR 322 DNA by the cyclic AMP receptor protein of Escherichia coli. J. Mol. Biol. 166, 93-98. pubmed PDF 40. Gronenborn, A.M. & Clore, G.M. (1983) Characterization of the DNA binding region recognized by dihydrofolate reductase from Lactobacillus casei. J. Biol. Chem. 258, 11256-11259. pubmed PDF 41. Clore, G.M. & Gronenborn, A.M. (1983) Theory of the time dependent transferred nuclear Overhauser effect: application to the structural analysis of ligand-protein complexes in solution. J. Magn. Reson. 53, 423-442. PDF 42. Clore, G.M., Kimber, B.J. & Gronenborn, A.M. (1983) The 1-1 hard pulse: a novel, simple and effective method of water resonance suppression in FT-1H-NMR. J. Magn. Reson. 54, 170-173. PDF 43. Barrett, A.N., Roberts, G.C.K., Burgen, A.S.V. & Clore, G.M. (1983) Ab initio molecular orbital calculations of electron distribution in the tetramethylammonium ion. Molec. Pharmacol. 24, 443-448. pubmed PDF 44. Martin, S.R., Gronenborn, A.M. & Clore, G.M. (1983) Specific DNA binding of the cAMP receptor protein to a synthetic oligodeoxyribonucleotide: a circular dichroism study. FEBS Lett. 159, 102-106. pubmed PDF 45. Gronenborn, A.M., Kimber, B.J., Clore, G.M. & McLaughlin, L.W. (1983) A nuclear magnetic resonance study of the ribotrinucleoside diphosphate UpUpC. Nucl. Magn. Res. 11, 5691-5699. pubmed PDF 46. Clore, G.M., Gronenborn, A.M. & Davies, R.W. (1983) Cooperative non-specific DNA binding of the N-terminal core of the cyclic AMP receptor protein of Escherichia coli and its modulation by cyclic AMP. FEBS Lett. 164, 57-612. pubmed PDF 47. Clore, G.M. & Gronenborn, A.M. (1983) Sequence dependent structural variations in two right handed alternating pyrimidine-purine DNA oligomers in solution determined by nuclear Overhauser enhancement measurements. EMBO J. 2, 2109-2115. pubmed PDF
48. Gronenborn, A.M., Clore, G.M., Jones, M.B. & Jiricny, J. (1984) A nuclear Overhauser enhancement study on the imino proton resonances of a DNA pentadecamer comprising the specific target site of the cyclic AMP receptor protein in the ara BAD operon. FEBS Lett. 165, 216-222. pubmed PDF 49. Clore, G.M., Gronenborn, A.M., Birdsall, B.M., Feeney, J. & Roberts, G.C.K. (1984) 19F-NMR studies of 3',5'-difluoromethotrexate binding to Lactobacillus casei dihydrofoate reductase: molecular motion and coenzyme induced conformational changes. Biochem. J. 217, 659-666. pubmed PDF 50. Gronenborn, A.M., Papadopoulos, P. & Clore, G.M. (1984) Immunochemical evidence for extensive ligand induced conformational changes in Lactobacillus casei dihydrofolate reductase. J. Biol. Chem. 259, 1082-1085. pubmed PDF 51. Antonjuk, D.J., Birdsall, B.M., Chang, H.T.A., Clore, G.M., Feeney, J., Gronenborn, A.M., Roberts, G.C.K. & Tran, T.Q. (1984) A 1H-NMR study of the role of the glutamate moiety in the binding of methotrexate to Lactobacillus casei dihydrofolate reductase. Bri. J. Pharmacol. 81, 309-315. pubmed 52. Gronenborn, A.M., Clore, G.M. & Jeffery, J. (1984) An unusual conformation of NAD+ bound to sorbitol dehydrogenase: a time dependent transferred nuclear Overhauser effect study. J. Mol. Biol. 172, 559-572. pubmed 53. Clore, G.M., Gronenborn, A.M. & McLaughlin, L.W. (1984) The structure of the ribotrinucleoside diphosphate codon UpUpC bound to tRNAPhe from yeast: a time dependent transferred nuclear Overhauser effect study. J. Mol. Biol. 174, 163-173. pubmed PDF 54. Clore, G.M. & Gronenborn, A.M. (1984) A Nuclear Overhauser enhancement study of the solution structure of a double stranded DNA undecamer comprising a portion of the specific target site for the cyclic AMP receptor protein in the gal operon: sequential resonance assignment. Eur. J. Biochem. 141, 119-129. pubmed PDF 55. Gronenborn, A.M., Clore, G.M. & Kimber, B.J. (1984) An investigation into the solution structures of two self-complementary DNA oligonucleotides 5'd-CGTACG and 5'd- ACGCGCGT by means of nuclear Overhauser enhancement measurements. Biochem. J. 221, 723-736. pubmed PDF 56. Clore, G.M., Gronenborn, A.M., Piper, E.A., McLaughlin, L.W., Graeser, E. & van Boom, J.H. (1984) The solution structure of a RNA pentadecamer comprising the anticodon loop and stem of yeast tRNAPhe: a 500 MHz 1H-NMR study. Biochem. J. 221, 737-751. pubmed PDF 57. Birdsall, B.M., Bevan, A.W., Pascual, C., Roberts, G.C.K., Feeney, J., Gronenborn, A.M. & Clore, G.M. (1984) Multinuclear NMR characterization of two coexisting conformational states of the Lactobacillus casei dihydrofolate reductase-trimethoprim-NADP+ complex. Biochemistry 23, 4733-4742. pubmed PDF 58. Gronenborn, A.M., Clore, G.M., Brunori, M., Giardina, B., Falcioni, G. & Perutz, M.F. (1984) Stereochemistry of ATP and GTP bound to fish haemoglobins: a transferred nuclear Overhauser enhancement, 31P-NMR, oxygen equilibrium and molecular modelling study. J. Mol. Biol. 178, 731-742. pubmed PDF 59. Clore, G.M. & Gronenborn, A.M. (1984) An investigation into the solution structure of the single stranded DNA undecamer 5'd- AAGTGTGATAT by means of nuclear Overhauser enhancement measurements. Eur. Biophys. J. 11, 95-102. pubmed 60. Clore, G.M. & Gronenborn, A.M. (1984) Internal mobility in a double stranded B DNA hexamer and undecamer: a time dependent proton-proton nuclear Overhauser enhancement study. FEBS Lett. 172, 219-225. pubmed PDF 61. Clore, G.M. & Gronenborn, A.M. (1984) Interproton distance measurements in solution for a double stranded DNA undecamer comprising a portion of the specific target site for the cyclic AMP receptor protein in the gal operon: a nuclear Overhauser enhancement study. FEBS Lett. 175, 117-123. pubmed PDF 62. Gronenborn, A.M., Clore, G.M., McLaughlin, L.W., Graeser, E., Lorber, B. & Giege, R. (1984) Yeast tRNAAsp - Codon and wobble codon-anticodon interactions: a transferred nuclear Overhauser enhancement study. Eur. J. Biochem. 145, 359-364. pubmed PDF 63. Gronenborn, A.M., Clore, G.M., Hobbs, L. & Jeffery, J. (1984) Glucose-6-phosphate dehydrogenase: a transferred nuclear Overhauser effect study of NADP+ conformations in enzyme-coenzyme binary complexes. Eur. J. Biochem. 145, 365-371. pubmed PDF 64. Clore, G.M., Lauble, H., Frenkiel, T.A. & Gronenborn, A.M. (1984) A two-dimensional NMR study of the solution structure of a DNA dodecamer comprising the consensus sequence for the specific DNA binding sites of the glucocorticoid receptor protein. Eur. J. Biochem. 145, 629-636. pubmed PDF 65. Gronenborn, A.M., Nermut, M.V., Eason, P. & Clore, G.M. (1984) Visualization of cAMP receptor protein induced DNA kinking by electron microscopy. J. Mol. Biol. 179, 751-757. pubmed PDF
66. Clore, G.M. & Gronenborn, A.M. (1985) Assessment of errors involved in the determination of interproton distance ratios and distances by means of one- and two-dimensional NOE measurements. J. Magn. Reson. 61, 158-164. PDF 67. Clore, G.M. & Gronenborn, A.M. (1985) Probing the three-dimensional structures of DNA and RNA oligonucleotides in solution by nuclear Overhauser enhancement measurements. FEBS Lett. 179, 187-198. pubmed PDF 68. Gronenborn, A.M. & Clore, G.M. (1985) Investigations into the solution structures of short nucleic acid fragments by means of nuclear Overhauser enhancement measurements. Progr. Nucl. Magn. Reson. Spectroscopy 17, 1-32. PDF 69. Andrews, J., Clore, G.M., Davies, R.W., Gronenborn, A.M., Gronenborn, B., Kalderon, D., Papadopoulos, P.C., Schafer, S., Sims, P.F.G. & Stancombe, R. (1985) Nucleotide sequence of the dihydrofolate reductase gene of methotrexate resistant Lactobacillus casei. Gene 35, 217-222. pubmed PDF 70. Perutz, M.F., Gronenborn, A.M., Clore, G.M., Hogg, J.H. & Shi, T. (1985) The pKa's of two histidines in human haemoglobin, the Bohr effect and the dipole moment of a-helices. J. Mol. Biol. 183, 491-498. pubmed PDF 71. Perutz, M.F., Gronenborn, A.M., Clore, G.M., Shi, T. & Craescu, C.T. (1985) Comparison of histidine proton magnetic resonances of human carbonmonoxy haemoglobin in different buffers. J. Mol. Biol. 186, 471-473. pubmed PDF 72. Clore, G.M. & Gronenborn, A.M. (1985) The solution structure of a B-DNA undecamer comprising a portion of the specific target site for the cyclic AMP receptor protein in the gal operon: refinement on the basis of interproton distance data. EMBO J. 4, 829-835. pubmed 73. Clore, G.M., Gronenborn, A.M., Moss, D.S. & Tickle, I.J. (1985) Refinement of the solution structure of the B-DNA hexamer 5'd(CGTACG)2 on the basis of interproton distance data. J. Mol. Biol. 185, 219-226. pubmed PDF 74. Clore, G.M., Gronenborn, A.M. & McLaughlin, L.W. (1985) The structure of the double stranded RNA pentamer 5'(CACAG).5'(CUGUG) by nuclear Overhauser enhancement measurements: interproton distance determination and structure refinement on the basis of X-ray coordinates. Eur. J. Biochem. 151, 153-165. pubmed PDF 75. Clore, G.M., Gronenborn, A.M., Brunger, A.T. & Karplus, M. (1985) The solution conformation of a heptadecapeptide comprising the DNA binding helix F of the cyclic AMP receptor protein of Escherichia coli: combined use of 1H-nuclear magnetic resonance and restrained molecular dynamics. J. Mol. Biol. 186, 435-455. pubmed PDF
76. Clore, G.M. & Gronenborn, A.M. (1986) Determination of three-dimensional structures of oligonucleotides in solution: combined use of nuclear Overhauser enhancement measurements and restrained least squares refinement. In Biomolecular Stereodynamics IV (Sarma, R.H., ed.) pp. 139-155, Adenine Press, New York. 77. Gronenborn, A.M. & Clore, G.M. (1986) The solution structure of RNA fragments by nuclear Overhauser enhancement measurements. In Structure and Dynamics of RNA, (van Knippenberg, R.H. & Hilbers, C.W., eds.) pp. 137-150, NATO ASI series, Plenum Press, New York. 78. Gronenborn, A.M. & Clore, G.M. (1986) Overproduction of the cAMP receptor protein of Escherichia coli and expression of the engineered carboxy-terminal DNA binding domain. Biochem. J. 236, 643-649. pubmed PDF 79. Clore, G.M., Gronenborn, A.M., Greipel, J. & Maass, G. (1986) The conformation of the single stranded DNA undecamer 5'd(AAGTGTGATAT) bound to single stranded DNA binding protein of Escherichia coli: a time dependent transferred nuclear Overhauser enhancement study. J. Mol. Biol. 187, 119-124. pubmed PDF 80. Nilsson, L., Clore, G.M., Gronenborn, A.M., Brunger, A.T. & Karplus, M. (1986) Structure refinement of oligonucleotides by molecular dynamics with NOE interproton distance restraints: application to 5'd(CGTACG)2. J. Mol. Biol. 188, 455-475. pubmed PDF 81. Clore, G.M., Gronenborn, A.M. Carlson, G. & Meyer, E.F. (1986) Stereochemistry of binding of the tetrapeptide Acetyl-Pro-Ala-Pro-TyrNH2 to porcine pancreatic elastase: combined use of two-dimensional transferred nuclear Overhauser enhancement measurements, restrained molecular dynamics, X-ray crystallography and molecular modelling. J. Mol. Biol. 190, 259-267. pubmed PDF 82. Brunger, A.T., Clore, G.M., Gronenborn, A.M. & Karplus, M. (1986) Three-dimensional structures of proteins determined by molecular dynamics with interproton distance restraints: application to crambin. Proc. Natl. Acad. Sci. U.S.A. 83, 3801-3805. pubmed PDF 83. Clore, G.M., Brunger, A.T., Karplus, M. & Gronenborn, A.M. (1986) Application of molecular dynamics with interproton distance restraints to three-dimensional protein structure determination: a model study of crambin. J. Mol. Biol. 191, 523-551. pubmed PDF 84. Clore, G.M., Martin, S.R. & Gronenborn, A.M. (1986) The solution structure of human growth hormone releasing factor: combined use of circular dichroism and nuclear magnetic resonance spectroscopy. J. Mol. Biol. 191, 553-561. pubmed PDF 85. Gronenborn, A.M., Clore, G.M., Schmeissner, U. & Wingfield, P.T. (1986) Sequence specific assignments of aromatic residues in the 1H-NMR spectrum of human interleukin-1b using site directed mutant proteins. Eur. J. Biochem. 161, 37-43. pubmed PDF 86. Zarbock, J., Clore, G.M. & Gronenborn, A.M. (1986) Nuclear magnetic resonance study of the globular domain of chicken histone H5: resonance assignment and secondary structure. Proc. Natl. Acad. Sci. U.S.A. 23, 7628-7632. pubmed PDF 87. Minter, S.J., Clore, G.M., Gronenborn, A.M. & Davies, R.W. (1986) Cooperative DNA binding by lambda integration protein - a key component of specificity. Eur. J. Biochem. 161, 727-731. pubmed PDF 88. Clore, G.M., Nilges, M., Sukumaran, D.K., Brunger, A.T., Karplus, M. & Gronenborn, A.M. (1986) The three-dimensional structure of a1-purothionin in solution: combined use of nuclear magnetic resonance, distance geometry and restrained molecular dynamics. EMBO J. 5, 2729-2735. PDF 89. MacDonald, H.R., Wingfield, P., Schmeissner, U., Shaw, A., Clore, G.M. & Gronenborn, A.M. (1986) Point mutations of human interleukin-1 with decreased receptor binding affinity. FEBS Lett. 209, 295-298. pubmed PDF
90. Clore, G.M., Sukumaran, D.K., Gronenborn, A.M., Teeter, M.M., Whitlow, M. & Jones, B.L. (1987) A nuclear magnetic resonance study of the solution structure of a1-purothionin: sequential resonance assignment, secondary structure and low resolution tertiary structure. J. Mol. Biol. 193, 571-578. pubmed PDF 91. Gent, M., Gronenborn, A.M., Davies, R.W. & Clore, G.M. (1987) Probing the sequence specific interaction of the cAMP receptor protein with DNA by site directed mutagenesis. Biochem. J. 242, 645-653. pubmed PDF 92. Sukumaran, D.K., Clore, G.M., Preu, A., Zarbock, J. & Gronenborn, A.M. (1987) A proton nuclear magnetic resonance study of hirudin: resonance assignment and secondary structure. Biochemistry 26, 333-338. PDF 93. Clore, G.M., Sukumaran, D.K., Nilges, M. & Gronenborn, A.M. (1987) The three-dimensional structure of phoratoxin in solution: combined use of nuclear magnetic resonance, distance geometry and restrained molecular dynamics. Biochemistry 26, 1732-1745. PDF 94. Brünger, A.T., Campbell, R.L., Clore, G.M., Gronenborn, A.M., Karplus, M., Petsko, G.A. & Teeter, M.M. (1987) Solution of a protein crystal structure with a model obtained from NMR interproton distance restraints. Science 235, 1049-1053. PDF 95. Clore, G.M., Sukumaran, D.K., Nilges, M., Zarbock, J. & Gronenborn, A.M. (1987) The conformations of hirudin in solution: a study using nuclear magnetic resonance, distance geometry and restrained molecular dynamics. EMBO J. 6, 529-537. PDF 96. Clore, G.M., Nilges, M., Brünger, A.T., Karplus, M. & Gronenborn, A.M. (1987) A comparison of the restrained molecular dynamics and distance geometry methods for determining three-dimensional structures of proteins on the basis of interproton distance restraints. FEBS Lett. 213, 269-277. pubmed PDF 97. Gronenborn, A.M., Bovermann, G. & Clore, G.M. (1987) A 1H-NMR study of the solution conformation of secretin: resonance assignment and secondary structure. FEBS Lett. 215, 88-94. pubmed PDF 98. Clore, G.M., Gronenborn, A.M., Nilges, M., Sukumaran, D.K. & Zarbock, J. (1987) The polypeptide fold of the globular domain of histone H5 in solution: a study using nuclear magnetic resonance, distance geometry and restrained molecular dynamics. EMBO J. 6, 1833-1842. pubmed PDF 99. Nilges, M., Clore, G.M., Gronenborn, A.M., Brunger, A.T., Karplus, M. & Nilsson, L. (1987) Refinement of the solution structure of the DNA hexamer 5'd(GCATGC)2: combined use of nuclear magnetic resonance and restrained molecular dynamics. Biochemistry 26, 3718-3733. pubmed PDF 100. Nilges, M., Clore, G.M., Gronenborn, A.M., Piel, N. & McLaughlin, L.W. (1987) Refinement of the solution structure of the DNA decamer 5'd(CTGGATCCAG)2: combined use of nuclear magnetic resonance and restrained molecular dynamics. Biochemistry 26, 3734-3744. pubmed PDF 101. Gent, M.E., Gartner, S., Gronenborn, A.M., Sandulache, R. & Clore, G.M. (1987) Site-directed mutants of the cAMP receptor protein - DNA binding of five mutant proteins. Protein Engineering 3, 201-203. pubmed 102. Shih, D.T., Perutz, F., Gronenborn, A.M. & Clore, G.M. (1987) Histidine proton resonances of carbonmonoxyhaemoglobins A and Cowtown in Chloride-free buffer. J. Mol. Biol. 195, 453-455. pubmed PDF 103. Clore, G.M., Gronenborn, A.M., Nilges, M. & Ryan, C.A. (1987) The three-dimensional structure of potato carboxypeptidase inhibitor in solution: a study using nuclear magnetic resonance, distance geometry and restrained molecular dynamics. Biochemistry 26, 8012-8023. pubmed PDF 104. Jansen, C., Gronenborn, A.M. & Clore, G.M. (1987) The binding of the cAMP receptor protein to synthetic DNA sites containing permutations in the concensus sequence TGTGA. Biochem. J. 246, 227-232. pubmed PDF 105. Nilges, M., Clore, G.M. & Gronenborn, A.M. (1987) A simple method for delineating well-defined and variable regions in protein structures determined from interproton distance data. FEBS Lett. 219, 11-16. PDF 106. Clore, G.M., Gronenborn, A.M., Kjær, M. & Poulsen, F.M. (1987) The determination of the three-dimensional structure of barley serine proteinase inhibitor 2 by nuclear magnetic resonance, distance geometry and restrained molecular dynamics. Protein Engineering 1, 305-311. pubmed 107. Clore, G.M., Gronenborn, A.M., James, M.N.G., Kjær, M., McPhalen, C.A. & Poulsen, F.M. (1987) Comparison of the solution and X-ray structures of barley serine proteinase inhibitor 2. Protein Engineering 1, 313-318. pubmed 108. Clore, G.M. & Gronenborn, A.M. (1987) Determination of three-dimensional structures of proteins in solution by nuclear magnetic resonance spectroscopy. Protein Engineering 1, 275-288. pubmed PDF 109. Wingfield, P., Mattaliano, R., MacDonald, H.R., Craig, S., Clore, G.M., Gronenborn, A.M. & Schmeissner, U. (1987) Recombinant derived interleukin-1a stabilized against specific deamidation. Protein Engineering 5, 413-417. pubmed 110. Bax, A., Sklenar, V., Clore, G.M. & Gronenborn, A.M. (1987) Water suppression in two-dimensional spin-locked NMR experiments using a novel phase cycling procedure. J. Am. Chem. Soc. 109, 6511-6513. PDF 111. Brünger, A.T., Clore, G.M., Gronenborn, A.M. & Karplus, M. (1987) Solution conformations of human growth hormone releasing factor: comparison of the restrained molecular dynamics and distance geometry methods for a system without long range distance data. Protein Engineering 1, 399-406. pubmed 112. Oschkinat, H., Clore, G.M., Nilges, M. & Gronenborn, A.M. (1987) Application of the z-COSY technique to macromolecules: measuring coupling constants with a modified pulse sequence. J. Magn. Reson. 75, 534-539. PDF
113. Meyer, E.F., Clore, G.M., Gronenborn, A.M. & Hansen, H.A.S. (1988) Analysis of an enzyme-substrate complex by X-ray crystallography and transferred nuclear Overhauser enhancement measurements: porcine pancreatic elastase and a hexapeptide. Biochemistry 27, 725-730. pubmed PDF 114. Clore, G.M., Nilges, M., Brünger, A.T. & Gronenborn, A.M. (1988) Determination of the backbone conformation of secretin by restrained molecular dynamics on the basis of interproton distance data. Eur. J. Biochem. 171, 479-484. pubmed PDF 115. Scalfi Happ, C., Happ, E., Nilges, M., Gronenborn, A.M. & Clore, G.M. (1988) Refinement of the solution structure of the ribonucleotide 5'r(GCAUGC)2: combined use of nuclear magnetic resonance and restrained molecular dynamics. Biochemistry 27, 1735-1743. pubmed PDF 116. Clore, G.M., Oschkinat, H., McLaughlin, L.W., Benseler, F., Scalfi Happ, C., Happ, E. & Gronenborn, A.M. (1988) Refinement of the solution structure of the DNA dodecamer 5'd(CGCGPATTCGCG)2 containing a stable purine-thymine base pair: combined use of nuclear magnetic resonance and restrained molecular dynamics. Biochemistry 27, 4185-4197. pubmed PDF 117. Allet, B., Payton, M., Mattaliano, R.J., Gronenborn, A.M., Clore, G.M. & Wingfield, P.T. (1988) The purification and characterization of the bacteriophage Mu DNA-binding protein ner. Gene 65, 259-268. pubmed PDF 118. Gronenborn, A.M., Sandulache, R., Gärtner, S. & Clore, G.M. (1988) Mutations in the cyclic AMP binding site of the cyclic AMP receptor protein of Escherichia coli. Biochem. J. 253, 801-807. pubmed PDF 119. Cieslar, C., Clore, G.M. & Gronenborn, A.M. (1988) Automatic phasing of pure phase absorption two-dimensional NMR spectra. J. Magn. Reson. 79, 154-157. PDF
121. Nilges, M., Clore, G.M. and Gronenborn, A.M. (1988) Determination of three-dimensional structures of proteins from interproton distance data by hybrid distance geometry-dynamical simulated annealing calculations. FEBS Lett 229, 317-324. pubmed PDF 122. Oschkinat, H., Griesinger, C., Kraulis, P.J., Sørensen, O.W., Ernst, R.R., Gronenborn, A.M. & Clore, G.M. (1988) Three-dimensional NMR spectroscopy of a protein in solution. Nature 332, 374-376. pubmed PDF 123. Nilges, M., Gronenborn, A.M., Brünger, A.T. & Clore, G.M. (1988) Determination of three-dimensional structures of proteins by simulated annealing with interproton distance restraints: application to crambin, potato carboxypeptidase inhibitor and barley serine proteinase inhibitor 2. Protein Engineering 2, 27-38. pubmed 124. Oschkinat, H., Clore, G.M. & Gronenborn, A.M. (1988) A two-dimensional nuclear Overhauser enhancement experiment using semiselective soft pulses and its applications to proteins. J. Magn. Reson. 78, 371-375. PDF 125. Holak, T.A., Engström, Å, Kraulis, P.J., Lindeberg, G., Bennich, H., Jones, T.A., Gronenborn, A.M. & Clore, G.M. (1988) The solution conformation of the antibacterial peptide cecropin A: a nuclear magnetic resonance and dynamical simulated annealing study. Biochemistry 27, 7620-7629. pubmed PDF 126. Holak, T.A., Nilges, M., Prestegard, H., Gronenborn, A.M. & Clore, G.M. (1988) Three-dimensional structure of acyl carrier protein in solution determined by nuclear magnetic resonance and the combined use of dynamical simulated annealing and distance geometry. Eur. J. Biochem. 175, 9-15. pubmed PDF 127. Gronenborn, A.M., Wingfield, P.T., McDonald, H.R., Schmeissner, U. & Clore, G.M. (1988) Site directed mutants of human interleukin-1a: a 1H-NMR and receptor binding study. FEBS Lett. 231, 135-138. pubmed PDF 128. Scalfi Happ, C., Happ, E., Clore, G.M. & Gronenborn, A.M. (1988) Refinement of the solution structure of the RNA-DNA hybrid 5'[r(GCA)d(TGC)]2: combined use of nuclear magnetic resonance and restrained molecular dynamics. FEBS Lett. 236, 62-70. pubmed PDF 129. Clore, G.M., Bax, A., Wingfield, P.T. & Gronenborn, A.M. (1988) Long range 15N-1H correlation as an aid to sequential proton resonance assignment of proteins: application to the DNA binding protein ner from phage Mu. FEBS Letters 238, 17-21. pubmed PDF 130. Zarbock, J., Gennaro, R., Romeo, D., Clore, G.M. & Gronenborn, A.M. (1988) A proton nuclear magnetic resonance study of the conformation of bovine anaphylatoxin C5a in solution. FEBS Letters 238, 289-294. pubmed PDF 131. Nilges, M., Clore, G.M. & Gronenborn, A.M. (1988) Determination of three-dimensional structures of proteins from interproton distance data by dynamical simulated annealing from a random array of atoms. FEBS Letters 239, 129-136. pubmed PDF 132. Garin, J., Vignais, P.V., Gronenborn, A.M., Clore, G.M., Gao, Z. & Baeuerlein, E. (1988) 1H-NMR studies on nucleotide binding to the catalytic sites of bovine mitochondrial F1-ATPase. FEBS Letters 242, 178-182. pubmed PDF
133. Driscoll, P.C., Clore, G.M., Beress, L. & Gronenborn, A.M. (1989) A proton nuclear magnetic resonance study of the anti-hypertensive and anti-viral protein BDS-I from the sea anemone Anemonia sulcata: sequential and stereospecific assignment and secondary structure. Biochemistry 28, 2178-2187. pubmed PDF 134. Driscoll, P.C., Gronenborn, A.M., Beress, L. & Clore, G.M. (1989) Determination of the three-dimensional structure of the anti-hypertensive and anti-viral protein BDS-I from the sea anemone Anemonia sulcata: a study using nuclear magnetic resonance and hybrid distance geometry-dynamical simulated annealing. Biochemistry 28, 2188-2198. pubmed PDF 135. Oschkinat, H., Cieslar, C., Gronenborn, A.M. & Clore, G.M. (1989) Three-dimensional homonuclear Hartmann Hahn-Nuclear Overhauser enhancement spectroscopy in H2O and its application to proteins. J. Magn. Reson. 81, 212-216. PDF 136. Folkers, P.J.M., Clore, G.M., Driscoll, P.C., Dodt, J., Köhler, S. & Gronenborn, A.M. (1989) The solution structure of recombinant hirudin and the Lys-47ÆGlu mutant: a nuclear magnetic resonance and hybrid distance geometry-dynamical simulated annealing study. Biochemistry 28, 2601-2617. pubmed PDF 137. Gronenborn, A.M., Bax, A., Wingfield, P.T. & Clore, G.M. (1989) A powerful method of sequential proton resonance assignment in proteins using relayed 15N-1H multiple quantum coherence spectroscopy. FEBS Letters 243, 93-98. pubmed PDF 138. Driscoll, P.C., Gronenborn, A.M. & Clore, G.M. (1989) The influence of stereospecific assignments on the determination of three-dimensional structures of proteins by nuclear magnetic resonance spectroscopy: application to the sea anemone protein BDS-I. FEBS Lett. 243, 223-233. pubmed PDF 139. Clore, G.M. & Gronenborn, A.M. (1989) Determination of three-dimensional structures of proteins and nucleic acids in solution by nuclear magnetic resonance spectroscopy. CRC Critical Reviews in Biochemistry and Molecular Biology 24, 479-564. pubmed 140. Clore, G.M., Nilges, M. & Gronenborn, A.M. (1989) Determination of three-dimensional structures of proteins in solution by dynamical simulated annealing with interproton distances derived from nuclear magnetic resonance spectroscopy. In Computer-Aided Molecular Design (Richards, W.G., ed.), pp. 203-219, IBC Technical Services, London. 141. Wingfield, P.T., Graber, P., Shaw, A.R., Gronenborn, A.M., Clore, G.M. & McDonald, H.R. (1989) Preparation, characterization and biochemical application of mutant interleukin-1b's with surface accessible cysteine residues. Eur. J. Biochem. 179, 565-571. pubmed PDF 142. Oschkinat, H., Cieslar, C., Holak, T.A., Clore, G.M. & Gronenborn, A.M. (1989) Practical and theoretical aspects of three-dimensional homonuclear Hartmann Hahn-nuclear Overhauser enhancement spectroscopy of proteins. J. Magn. Reson. 83, 450-472. PDF 143. Gronenborn, A. M., Wingfield, P. T. & Clore, G. M. (1989) Determination of the secondary structure of the DNA binding protein Ner from phage Mu using 1H homonuclear and 15N-1H heteronuclear NMR spectroscopy. Biochemistry 28, 5081-5089. pubmed PDF 144. Gronenborn, A.M. & Clore, G.M. (1989) Analysis of the relative contributions of the nuclear Overhauser interproton distance restraints and the empirical energy function in the calculation of oligonucleotide structures using restrained molecular dynamics. Biochemistry 28, 5978-5984. pubmed PDF 145. Forman-Kay, J.D., Clore, G.M., Driscoll, P.C., Wingfield, P.T., Richards, F.M. & Gronenborn, A.M. (1989) A proton nuclear magnetic resonance assignment and secondary structure determination of recombinant human thioredoxin. Biochemistry 28, 7088-7097. pubmed PDF 146. Kraulis, P.J., Clore, G.M., Nilges, M., Jones, T.A., Pettersson, G., Knowles, J. & Gronenborn, A.M. (1989) Determination of the three-dimensional solution structure of the C-terminal domain of cellobiohydrolase I from Trichoderma reesei: a study using nuclear magnetic resonance and hybrid distance geometry-dynamical simulated annealing. Biochemistry 28, 7241-7257. pubmed PDF 147. Clore, G.M. & Gronenborn, A.M. (1989) How accurately can interproton distances in macromolecules really be determined by full relaxation matrix analysis of nuclear Overhauser enhancement data? J. Magn. Reson. 84, 398-409. PDF 148. Marion, D., Driscoll, P.C., Kay, L.E., Wingfield, P.T., Bax, A., Gronenborn, A.M. & Clore, G.M. (1989) Overcoming the overlap problem in the assignment of 1H-NMR spectra of larger proteins using three-dimensional heteronuclear 1H-15N Hartmann-Hahn and nuclear Overhauser - multiple quantum coherence spectroscopy: application to interleukin-1b. Biochemistry 28, 6150-6156. pubmed PDF 149. Clore, G.M., Appella, E., Yamada, M., Matsushima, K. & Gronenborn, A.M. (1989) Determination of the secondary structure of interleukin-8 by nuclear magnetic resonance spectroscopy. J. Biol. Chem. 264, 18907-18911. pubmed PDF
150. Gronenborn, A.M., Nilges, M., Peanasky, R.J. & Clore, G.M. (1990) Sequential resonance assignment and secondary structure determination of the Ascaris trypsin inhibitor, a member of a novel class of proteinases inhibitors. Biochemistry 29, 183-189. pubmed PDF 151. Nilges, M., Clore, G.M. & Gronenborn, A.M. (1990) 1H-NMR stereospecific assignments by conformational database searches. Biopolymers 29, 813-822. pubmed 152. Clore, G.M. & Gronenborn, A.M. (1990) Extending the limits of protein structure determination by NMR. In Theoretical Biochemistry and Molecular Biophysics: a Comprehensive Survey, (Beveridge, D.L. and Lavery, L., eds.), vol. 2, pp. 1-16, Adenine Press, New York, 153. Forman-Kay, J.D., Gronenborn, A.M., Kay, L.E., Wingfield, P.T. & Clore, G.M. (1990) Studies on the solution conformation of human thioredoxin using heteronuclear 15N-1H nuclear magnetic resonance spectroscopy. Biochemistry 29, 1566-1572. pubmed PDF 154. Gronenborn, A.M. & Clore, G.M. (1990) Protein structure determination in solution by two-dimensional and three-dimensional nuclear magnetic resonance spectroscopy. Analytical Chemistry 62, 2-15. pubmed PDF 155. Driscoll, P.C., Clore, G.M., Marion, D., Wingfield, P.T. & Gronenborn, A.M. (1990) Complete resonance assignment for the polypeptide backbone of interleukin-1b using three-dimensional heteronuclear NMR spectroscopy. Biochemistry 29, 3542-3556. pubmed PDF 156. Driscoll, P.C., Gronenborn, A.M., Wingfield, P.T. & Clore, G.M. (1990) Determination of the secondary structure and molecular topology of interleukin-1b using two- and three-dimensional heteronuclear 15N-1H NMR spectroscopy. Biochemistry 29, 4468-4682. pubmed PDF 157. Clore, G.M., Appella, E., Yamada, M., Matsushima, K. & Gronenborn, A.M. (1990) The three-dimensional structure of interleukin-8 in solution. Biochemistry 29, 1689-1696. pubmed PDF 158. Bax, A., Clore, G.M., Driscoll, P.C., Gronenborn, A.M., Ikura, M. & Kay, L.E. (1990) Practical aspects of proton-carbon-carbon-proton three-dimensional correlation spectroscopy of 13C--labeled proteins. J. Magn. Reson. 87, 620-628. PDF 159. Bax, A., Clore, G.M. & Gronenborn, A.M. (1990) 1H-1H correlation via isotropic mixing of 13C magnetization: a new three-dimensional approach for assigning 1H and 13C spectra of 13C-enriched proteins. J. Magn. Reson. 88, 425-431. PDF 160. Clore, G.M., Szabo, A., Bax, A., Kay, L.E., Driscoll, P.C. & Gronenborn, A.M. (1990) Deviations from the simple two parameter model free approach to the interpretation of 15N nuclear magnetic relaxation of proteins. J. Am. Chem. Soc. 112, 4989-4991. PDF 161. Clore, G.M., Driscoll, P.C., Wingfield, P.T. & Gronenborn, A.M. (1990) Low resolution structure of interleukin-1b in solution derived from 1H-15N heteronuclear three-dimensional NMR spectroscopy. J. Mol. Biol. 214, 811-817. pubmed PDF 162. Clore, G.M., Driscoll, P.C., Wingfield, P.T. & Gronenborn, A.M. (1990) Analysis of backbone dynamics of interleukin-1b using two-dimensional inverse detected heteronuclear 15N-1H NMR spectroscopy. Biochemistry 29, 7387-7401. pubmed PDF 163. Clore, G.M., Bax, A., Wingfield, P.T. & Gronenborn, A.M. (1990) Identification and localization of bound internal water in the solution structure of interleukin-1b by heteronuclear three-dimensional 1H rotating frame Overhauser 15N-1H multiple quantum coherence NMR spectroscopy. Biochemistry 29, 5671-5676. pubmed PDF 164. Clore, G.M., Bax, A., Driscoll, P.C., Wingfield, P.T. & Gronenborn, A.M. (1990) Assignment of the side chain 1H and 13C resonance of interleukin-1b using double and triple resonance heteronuclear three-dimensional NMR spectroscopy. Biochemistry 29, 8172-8184. pubmed PDF 165. Kay, L.E., Clore, G.M., Bax, A. & Gronenborn, A.M. (1990) Four-dimensional heteronuclear triple resonance NMR spectroscopy of interleukin-1b in solution. Science 249, 411-414. pubmed PDF 166. Omichinski, J., Clore, G.M., Appella, E., Sakaguchi, K. & Gronenborn, A.M. (1990) High resolution three-dimensional solution structure of a single zinc finger from a human enhancer binding protein in solution. Biochemistry 29, 9324-9334. pubmed PDF 167. Becerra, S.P., Clore, G.M., Gronenborn, A.M., Karlström, A., Stahl, S.J., Wilson, S.H. & Wingfield, P.T. (1990) Purification and characterization of the RNase H domain of HIV-1 reverse transcriptase expressed in recombinant Escherichia coli. FEBS Lett. 270, 76-80. pubmed PDF 168. Ikura, M., Bax, A., Clore, G.M. & Gronenborn, A.M. (1990) Detection of nuclear Overhauser effects between degenerate amide proton resonances by heteronuclear three-dimensional NMR spectroscopy. J. Am. Chem. Soc.112, 9020-9022. PDF
169. Clore, G.M., Kay, L.E., Bax, A. & Gronenborn, A.M. (1991) Four dimensional 13C/13C-edited nuclear Overhauser enhancement spectroscopy of a protein in solution: application to interleukin-1b. Biochemistry 30, 12-18. pubmed PDF 170. Clore, G.M. & Gronenborn, A.M. (1991) Two, three and four dimensional NMR methods for obtaining larger and more precise three-dimensional structures of proteins in solution. Ann. Rev. Biophys. Biophys. Chem. 20, 29-63. pubmed PDF 171. Clore, G.M. & Gronenborn, A.M. (1991) Comparison of NMR and X-ray structures of hirudin. In Computational Aspects of the Study of Biological Macromolecules by Nuclear Magnetic Resonance Spectroscopy, (ed. Hoch, J.C.), pp. 57-66, NATO ASI Series, Plenum Press. 172. Forman-Kay, J.D., Clore, G.M., Wingfield, P.T. & Gronenborn, A.M. (1991) The high resolution three-dimensional structure of reduced recombinant human thioredoxin in solution. Biochemistry 30, 2685-2698. pubmed PDF 173. Baldwin, E.T., Weber, I.T., St. Charles, R., Xuan, J.C., Appella, E., Yamada, M., Matsushima, K., Edwards, B.F.P., Clore, G.M., Gronenborn, A.M. & Wlodawer, A. (1991) Crystal structure of interleukin-8: symbiosis of NMR and crystallography. Proc. Natl. Acad. Sci. U.S.A. 88, 502-506. pubmed PDF 174. Clore, G.M. & Gronenborn, A.M. (1991) Comparison of the solution nuclear magnetic resonance and crystal structures of interleukin-8: possible implications for the mechanism of receptor binding. J. Mol. Biol. 217, 611-620. pubmed PDF 175. Gronenborn, A.M. & Clore, G.M. (1991) Modeling the three-dimensional structure of the monocyte chemoattractant and activating protein MCAF/MCP-1 on the basis of the solution structure of interleukin-8. Protein Engineering 4, 263-269. pubmed 176. Clore, G.M., Bax, A. & Gronenborn, A.M. (1991) Stereospecific assignment of b-methylene protons in larger proteins using three-dimensional 15N-separated Hartmann-Hahn and 13C-separated rotating frame Overhauser spectroscopy. J. Biomol. NMR 1, 13-22. pubmed PDF 177. Clore, G.M., Wingfield, P.T. & Gronenborn, A.M. (1991) High resolution three dimensional structure of interleukin-1b in solution by three and four dimensional nuclear magnetic resonance spectroscopy. Biochemistry 30, 2315-2323. pubmed PDF 178. Clore, G.M. & Gronenborn, A.M. (1991) NMR and X-ray analysis of the three-dimensional structure of interleukin-8. In Neutrophil-Activating Peptides and other Chemotactic Cytokines, (Baggiolini, M. & Sorg, C., eds.) 4, 18-40, S. Karger, Basel 179. Clore, G.M. & Gronenborn, A.M. (1991) Applications of three- and four-dimensional heteronuclear NMR spectroscopy to protein structure determination. Progr. Nucl. Magn. Reson. Spectroscopy 23, 43-92. PDF 180. Sakaguchi, K., Appella, E., Omichinski, J.G., Clore, G.M. & Gronenborn, A.M. (1991) Specific DNA binding to an MHC enhancer sequence by a synthetic 57-residue double zinc finger peptide from a human enhancer binding protein. J. Biol. Chem. 266, 7306-7311. pubmed PDF 181. Clore, G.M., Omichinski, J.G. & Gronenborn, A.M. (1991) Slow conformational dynamics at the metal coordination site of a zinc finger. J. Am. Chem. Soc. 113, 4350-4351. PDF 182. Clore, G.M. & Gronenborn, A.M. (1991) Structures of larger proteins in solution: three- and four-dimensional heteronuclear NMR spectroscopy. Science 252, 1390-1399. pubmed PDF 183. Forman-Kay, J.D., Gronenborn, A.M., Wingfield, P.T. & Clore, G.M. (1991) Determination of the positions of bound water in the solution structure of reduced human thioredoxin by heteronuclear three-dimensional nuclear magnetic resonance spectroscopy. J. Mol. Biol. 220, 209-216. pubmed PDF 184. Clore, G.M. & Gronenborn, A.M. (1991) Comparison of the solution nuclear magnetic resonance and X-ray crystal structures of human recombinant interleukin-1b. J. Mol. Biol. 221, 47-53. pubmed PDF 185. Powers, R., Gronenborn, A.M., Clore, G.M. & Bax, A. (1991) Three-dimensional triple resonance NMR of 13C/15N enriched proteins using constant-time evolution. J. Magn. Reson. 94, 209-213. PDF 186. Gronenborn, A.M., Filpula, D.R., Essig, N.Z., Achari, A., Whitlow, M., Wingfield, P.T. & Clore, G.M. (1991) A novel highly stable fold of the immunoglobulin binding domain of Streptococcal protein G. Science 253, 657-661. pubmed PDF 187. Powers, R., Clore, G.M., Bax, A., Garrett, D.S., Stahl, S.J., Wingfield, P.T. & Gronenborn, A.M. (1991) Secondary structure of the ribonuclease H domain of the human immunodificiency virus reverse transcriptase in solution using three-dimensional double and triple resonance heteronuclear magnetic resonance spectroscopy. J. Mol. Biol. 221, 1081-1090. pubmed PDF 188. Garrett, D.S., Powers, R., Gronenborn, A.M. & Clore, G.M. (1991) A common sense approach to peak picking two-, three- and four-dimensional spectra using automatic computer analysis of contour diagrams. J. Magn. Reson. 95, 214-220. PDF 189. Omichinski, J.G., Clore, G.M., Sakaguchi, K., Appella, E. & Gronenborn, A.M. (1991) Structural characterization of a 39-residue synthetic peptide containing the two zinc binding domains from the HIV-1 p7 nucleocapsid protein by CD and NMR spectroscopy. FEBS Lett. 292, 25-30. pubmed PDF 190. Gronenborn, A.M. & Clore, G.M. (1991) Similarity of Protein G and Ubiquitin. Science 254, 581-582. PDF
191. Clore, G.M. & Gronenborn, A.M. (1992) Localization of bound water in the solution structure of the immunoglobulin binding domain of Streptococcal protein G: evidence for solvent induced helical distortions in solution. J. Mol. Biol. 223, 853-856. pubmed PDF 192. Grzesiek, S., Ikura, M., Clore, G.M., Gronenborn, A.M. & Bax, A. (1992) A 3D triple resonance NMR technique for qualitative measurement of carbonyl-Hb J couplings in isotopically enriched proteins. J. Magn. Reson. 96, 215-221. PDF 193. Clore, G.M. & Gronenborn, A.M. (1992) Practical aspects of two, three and four-dimensional nuclear magnetic resonance spectroscopy applied to the study of protein structure. In Protein Engineering - a Practical Approach, (eds. Rees, A.R., Wetzel, R. & Sternberg, M.J.E.), pp. 33-56, Oxford University Press. 194. Lozier, R.H., Xie, A., Hofrichter, J. & Clore, G.M. (1992) Reversible steps in the bacteriorhodopsin photocycle. Proc. Natl. Acad. Sci. 89, 3610-3614. pubmed PDF 195. Omichinski, J.G., Clore, G.M., Robien, M., Sakaguchi, K., Appella, E. & Gronenborn, A.M. (1992) High resolution solution structure of the double Cys2His2 zinc finger from the human enhancer binding protein MBP-1. Biochemistry 31, 3907-3917. pubmed PDF 196. Forman-Kay, J.D., Clore, G.M. & Gronenborn, A.M. (1992) The relationship between electrostatics and redox function in human thioredoxin: charaterization of pH titration shifts using two-dimensional homo- and heteronuclear NMR. Biochemistry 31, 3442-3452. pubmed PDF 197. Robien, M.A., Clore, G.M., Omichinski, J.G., Perham, R.N., Appella, E., Sakaguchi, K. & Gronenborn, A.M. (1992) Three-dimensional solution structure of the E3-binding domain of the dihydrolipoamide succinyltransferase core from the 2-oxoglutarate dehydrogenase multienzyme complex of Escherichia coli. Biochemistry 31, 3463-3471. pubmed PDF 198. Powers, R., Garrett, D.S., March, C.J., Frieden, E.A., Gronenborn, A.M. & Clore, G.M. (1992) 1H, 15N, 13C and 13CO assignments of human interleukin-4 using three-dimensional double and triple resonance heteronuclear magnetic resonance spectroscopy. Biochemistry 31, 4334-4347. pubmed PDF 199. Garrett, D.S., Powers, R., March, C.J., Frieden, E.A., Clore, G.M. & Gronenborn, A.M. (1992) Determination of the secondary structure and folding topology of human interleukin-4 using three-dimensional heteronuclear magnetic resonance spectroscopy. Biochemistry 31, 4347-4353. pubmed PDF 200. Chandrasasekhar, I., Clore, G.M., Szabo, A., Gronenborn, A.M. & Brooks, B.R. (1992) A 500 ps molecular dynamics simulation study of interleukin-1b in water: correlation with nuclear magnetic resonance spectroscopy and crystallography. J. Mol. Biol. 226, 239-250. pubmed PDF 201. Ikura, M., Clore, G.M., Gronenborn, A.M., Zhu, G., Klee, C.B. & Bax, A. (1992) Solution structure of a calmodulin-target peptide complex by multi-dimensional NMR. Science 256, 632-638. pubmed PDF 202. Powers, R., Garrett, D.S., March, C.J., Frieden. E.A., Gronenborn, A.M. & Clore, G.M. (1992) Three-dimensional solution structure of human interleukin-4 by multi-dimensional heteronuclear magnetic resonance spectroscopy. Science 256, 1673-1677. pubmed PDF 203. Forman-Kay, J.D., Clore, G.M., Stahl, S.J. & Gronenborn, A.M. (1992) 1H and 15N resonance assignments and secondary structure of the human thioredoxin C62A, C69A, C73A mutant. J. Biomolec. NMR 2, 431-445. pubmed 204. Achari, A., Hale, S.P, Howard, A.J., Clore, G.M., Gronenborn, A.M., Hardman, K.D. & Whitlow, M. (1992) The 1.67 Å X-ray structure of the B2 immunoglobulin domain of streptococcal protein G and comparison to the NMR structure of the B1 domain. Biochemistry 31, 10449-10457. pubmed PDF 205. Shaanan, B., Gronenborn, A.M., Cohen, G.H., Gilliland, G.L., Veerapandian, B., Davies, D.R. & Clore, G.M. (1992) Combining experimental information from crystal and solution studies: joint X-ray and NMR refinement. Science 257, 961-964. pubmed PDF 206. Rose, K., Simona, M.G., Savoy, L.A., Regamey, P.O., Green, B.N., Clore, G.M., Gronenborn, A.M. & Wingfield, P.T. (1992) Pyruvic acid is attached through its central carbon atom to the amino terminus of the recombinant-DNA derived DNA-binding protein Ner of bacteriophage Mu. J. Biol. Chem. 267, 19101-19106. pubmed PDF 207. Powers, R., Clore, G.M., Stahl, S.J., Wingfield, P.T. & Gronenborn, A.M. (1992) Analysis of the backbone dynamics of the ribonuclease H domain of the human immunodeficiency virus reverse transcriptase using 15N relaxation measurements. Biochemistry 31, 9150-9157. pubmed PDF
208. Omichinski, J.G., Trainor, C., Evans, T., Gronenborn, A.M., Clore, G.M. & Felsenfeld, G. (1993) A small single-'finger' peptide from the erythroid factor GATA-1 binds specifically to DNA as a zinc or iron complex. Proc. Natl. Acad. Sci. U.S.A. 90, 1676-1680. pubmed PDF 209. Grasberger, B.L., Gronenborn, A.M. & Clore, G.M. (1993) Analysis of the backbone dynamics of interleukin-8 by 15N relaxation measurements. J. Mol. Biol. 230, 364-372. pubmed PDF 210. Clore, G.M., Robien, M.A. & Gronenborn, A.M. (1993) Exploring the limits of precision and accuracy of protein structures determined by nuclear magnetic resonance spectroscopy. J. Mol. Biol. 231, 82-102. pubmed PDF 211. Vuister, G.W., Clore, G.M., Gronenborn, A.M., Powers, R., Garrett, D.S., Tschudin, R. & Bax, A. (1993) Increased resolution and improved spectral quality in four-dimensional 13C/13C-separated HMQC-NOE-HMQC spectra using pulsed field gradients. J. Magn. Reson. Series B 101, 210-213. PDF 212. Sakaguchi, K., Zambrano, N., Baldwin, E.T., Shapiro, B.A., Erickson, J.W., J.G. Omichinski, G.M. Clore, A.M. Gronenborn & E. Appella (1993) Identification of a binding site for the human immunodeficiency virus type I nucleocapsid protein. Proc. Natl. Acad. Sci. U.S.A. 90, 5219-5223. pubmed PDF 213. Varley, P., Gronenborn, A.M., Christensen, H., Wingfield, P.T., Pain, R.H. & Clore, G.M. (1993) Kinetics of folding of the all b-sheet protein interleukin-1b studied by nuclear magnetic resonance, circular dichroism and fluorescence. Science 240, 1110-1113. pubmed PDF 214. Powers, R., Clore, G.M., Garrett, D.S. & Gronenborn, A.M. (1993) Relationships between the precision of high resolution protein NMR structures, solution order parameters and crystallographic B factors. J. Magn. Reson. Series B 101, 325-327. PDF 215. Gronenborn, A.M. & Clore, G.M. (1993) Structural studies of immunoglobulin binding domains of Streptococcal Protein G. ImmunoMethods 2, 3-8. PDF 216. Powers, R., Garrett, D.S., March, C.J., Frieden, E.A., Gronenborn, A.M. & Clore, G.M. (1993) The high resolution three-dimensional solution structure of human interleukin-4 determined by multi-dimensional heteronuclear magnetic resonance spectroscopy. Biochemistry 32, 6744-6762. pubmed PDF 217. Gronenborn, A.M. & Clore, G.M. (1993) Identification of the contact surface of a Streptococcal protein G domain complexed with a human Fc fragment. J. Mol. Biol.233, 331-335. pubmed PDF 218. Clore, G.M. & Gronenborn, A.M. (1993) Structural studies of interleukin-1b, interleukin-4 and interleukin-8, ImmunoMethods 3, 56-81. PDF 219. Brünger, A.T., Clore, G.M., Gronenborn, A.M., Saffrich, R. & Nilges, M. (1993) Assessing the quality of solution nuclear magnetic resonance structures by complete cross-validation. Science 261, 328-331. pubmed PDF 220. Omichinski, J.G., Clore, G.M., Schaad, O., Felsenfeld, G., Trainor, C., Appella, E., Stahl, S.J. & Gronenborn, A.M. (1993) NMR structure of a specific DNA complex of Zn-containing DNA binding domain of GATA-1. Science 261, 438-446. pubmed PDF 221. Clore, G.M., Bax, A., Ikura, M. & Gronenborn, A.M. (1993) Structure of calmodulin-target peptide complexes. Current Opinion in Structural Biology 3, 838-845. PDF
222. Bax, A., Grzesiek, S., Gronenborn, A.M. & Clore, G.M. (1994) Isotope-filtered 2D HOHAHA spectroscopy of a peptide-protein complex using heteronuclear Hartmann-Hahn dephasing. J. Magn. Reson. 106 Series A, 269-273. PDF 223. Gronenborn, A.M. & Clore, G.M. (1994) Experimental support for the "hydrophobic zipper" hypothesis of protein folding. Science 263, 536. pubmed PDF 224. Barchi, J.J., Grasberger, B., Gronenborn, A.M. & Clore, G.M. (1994) Investigation of the backbone dynamics of the IgG-binding domain of Streptococcal Protein G by heteronuclear two-dimensional 1H-15N nuclear magnetic resonance spectroscopy. Protein Science 3, 15-21. pubmed PDF 225. Clore, G.M., Bax, A., Omichinski, J.G. & Gronenborn, A.M. (1994) Localization of bound water in the solution structure of the specific complex of the erythroid transcription factor GATA-1 with DNA by water selective two-dimensional heteronuclear magnetic resonance spectroscopy. Structure 2, 89-94. pubmed PDF 226. Clubb, R.T., Omichinski, J.G., Clore, G.M. & Gronenborn, A.M. (1994) Mapping the binding surface of interleukin-8 complexed with an N-terminal fragment of the type I human interleukin-8 receptor. FEBS Lett. 338, 93-97. pubmed PDF 227. Garrett, D.S., Lodi, P.J., Shamoo, Y., Williams, K.R., Clore, G.M. & Gronenborn, A.M. (1994) Determination of the secondary structure and folding topology of a RNA binding domain of the mammalian hnRNP A1 protein using three-dimensional heteronuclear magnetic resonance spectroscopy. Biochemistry 33, 2852-2858. pubmed PDF 228. Clore, G.M. & Gronenborn, A.M. (1994) Structures of larger proteins, protein-ligand and protein-DNA complexes by multi-dimensional heteronuclear NMR. Protein Science 3, 372-390 pubmed PDF; Progr. Biophys. Mol. Biol. 62, 153-184 pubmed PDF; In Encyclopedia of Nuclear Magnetic Resonance, vol. 7, pp. 4602-4622, (eds. Grant, D.M. & Harris, R.K.), John Wiley & Sons, New York (1996). 229. Rozwarski, D.A., Gronenborn, A.M., Clore, G.M., Bazan, J.F., Bohm, A., Wlodawer, A., Hatada, M. & Karplus, P.A. (1994) Structural comparison among the short-chain helical cytokines. Structure 2, 159-173. pubmed PDF 230. Lodi, P.J., Garrett, D.S., Kuszewski, J., Tsang, M.L.S., Weatherbee, J.A., Leonard, W.J., Gronenborn, A.M. & Clore, G.M. (1994) High resolution solution structure of the b chemokine hMIP-1b by multi-dimensional NMR. Science 263, 1762-1767. pubmed PDF 231. Garrett, D.S., Kuszewski, J., Hancock, T.J., Lodi, P.J., Vuister, G.W., Gronenborn, A.M. & Clore, G.M. (1994) The impact of direct refinement against three-bond HN-CaH coupling constants on protein structure determination by NMR. J. Magn. Reson. Series B 104, 99-103. pubmed PDF 232. Gronenborn, A.M. & Clore, G.M. (1994) Identification of N-terminal helix capping boxes by means of 13C chemical shifts. J. Biomol. NMR 4, 455-458. pubmed 233. Smith, L.J., Redfield, C., Smith, R.A.G., Dobson, C.M., Clore, G.M., Gronenborn, A.M., Walter, M.R., Naganbushan, T.L. & Wlodawer, A. (1994) Comparison of four independently determined structures of human recombinant interleukin-4. Nature Struct. Biol. 1, 301-310. pubmed PDF 234. Werner, M.H., Clore, G.M., Gronenborn, A.M., Kondoh, A. & Fisher, R.J. (1994) Refolding proteins by gel filtration chromatography. FEBS Lett. 345, 125-130. pubmed PDF 235. Qin, J., Clore, G.M. & Gronenborn, A.M. (1994) The high resolution three-dimensional solution structure of the oxidized and reduced states of human thioredoxin: delineation of conformational differences between the two redox states. Structure 2, 503-522. pubmed PDF 236. Werner, M.W., Clore, G.M., Gronenborn, A.M. & Nash, H.A. (1994) Symmetry and asymmetry in the function of Escherichia coli integration host factor. Current Biology 4, 477-487. pubmed PDF 237. Grasberger, B.L., Clore, G.M. & Gronenborn, A.M. (1994) High-resolution structure of Ascaris trypsin inhibitor in solution: direct evidence for a pH induced conformational transition in the reactive site. Structure 2, 669-678. pubmed PDF 238. Makhatadze, G.I., Clore, G.M., Gronenborn, A.M. & Privalov, P.L. (1994) Thermodynamics of unfolding of the all b-sheet protein interleukin-1b. Biochemistry 33, 9327-9332. pubmed PDF 239. Clore, G.M. & Gronenborn, A.M. (1994) Multidimensional heteronuclear nuclear magnetic resonance of proteins.Meth. Enzymol. 239, 349-363; Spectroscopy 10, 32-38 (1995); In Encyclopedia of Nuclear Magnetic Resonance, vol. 7, pp. 4744-4752, (eds. Grant, D.M. & Harris, R.K.), John Wiley & Sons, New York (1996). pubmed 240. Gronenborn, A.M. & Clore, G.M. (1994) Where is NMR taking us. Proteins: Struct. Funct. Genet. 19, 273-276. pubmed 241. Clore, G.M., Omichinski, J.G., Sakaguchi, K., Zambrano, N., Sakamoto, H., Appella, E. & Gronenborn, A.M. (1994) High-resolution solution structure of the oligomerization domain of p53 by multi-dimensional NMR. Science 265, 386-391. pubmed PDF 242. Wang, A.C., Lodi, P.J., Qin, J., Vuister, G.W., Gronenborn, A.M. & Clore, G.M. (1994) An efficient triple-resonance experiment for proton-directed sequential backbone assignment of medium-sized proteins. J. Magn. Reson. Series B 105, 196-198. pubmed PDF 243. Gronenborn, A.M. & Clore, G.M. (1994) Structural studies of interleukin-8 and interleukin-4. In Structural Biology: The State of the Art, (Sarma, R.H. & Sarma, M.H., eds.) pp. 19-42, Adenine Press, New York. 244. Covell, D.G., Smythers, G.W., Gronenborn, A.M. & Clore, G.M. (1994) Analysis of hydrophobicity in the a and b chemokine families and its relevance to dimerization. Protein Science 3, 2064-2072. pubmed PDF 245. Kuszewski, J., Clore, G.M. & Gronenborn, A.M. (1994) Fast folding of a prototypic polypeptide: the immunoglobulin binding domain of Streptococcal Protein G. Protein Science 3, 1945-1952. pubmed PDF 246. Clubb, R.T., Omichinski, J.G., Savilahti, H., Mizuuchi, K., Gronenborn, A.M. & Clore, G.M. (1994) A novel class of winged helix-turn-helix protein - the DNA binding domain of Mu transposase. Structure 2, 1041-1048. pubmed PDF
247. Clore, G.M. & Gronenborn, A.M. (1995) Three-dimensional structures of a and b chemokines. FASEB Journal 9, 57-62. pubmed PDF 248. Kuszewski, J., Qin, J., Gronenborn, A.M. & Clore, G.M. (1995) The impact of direct refinement against 13Ca and 13Cb chemical shifts on protein structure determination by NMR. J. Magn. Reson Series B 106, 92-96. pubmed PDF 249. Ernst, J.A., Clubb, R.T., Zhou, H.-X., Gronenborn, A.M. & Clore, G.M. (1995) Demonstration of positionally disordered water within a protein hydrophobic cavity by NMR. Science 267, 1813-1817. pubmed PDF 250. Clore, G.M., Omichinski, J.G., Sakaguchi, K., Zambrano, N., Sakamoto, H., Appella, E. & Gronenborn, A.M. (1995) Interhelical angles in the solution structure of the oligomerization domain of the tumour suppressor p53. Science 267, 1515-1516. pubmed PDF 251. Strzelecka, T.E., Hayes, J.J., Clore, G.M. & Gronenborn, A.M. (1995) DNA binding specificity of the Mu Ner protein. Biochemistry 34, 2946-2955. pubmed PDF 252. Qin, J., Clore, G.M. Kennedy, W.M.P., Huth, J.R. & Gronenborn, A.M. (1995) Solution structure of human thioredoxin in a mixed disulfide intermediate complex with its target peptide from the transcription factor NFkB. Structure 3, 289-297. pubmed PDF 253. Clore, G.M., Ernst, J., Clubb, R.T., Omichinski, J.G., Kennedy, W.M.P., Sakaguchi, K., Appella, E. & Gronenborn, A.M. (1995) Refined solution structure of the oligomerization domain of the tumour suppressor p53. Nature Struct. Biol. 2, 321-332. pubmed PDF 254. Clubb, R.T., Omichinski, J.G., Sakaguchi, K., Appella, E., Gronenborn, A.M. & Clore, G.M. (1995) Backbone dynamics of the oligomerization domain of p53 determined from 15N NMR relaxation measurements. Protein Science 4, 855-862. pubmed PDF 255. Kuszewski, J., Gronenborn, A.M. & Clore, G.M. (1995) The impact of direct refinement against proton chemical shifts in protein structure determination by NMR. J. Magn. Reson. Series B 107, 293-297. pubmed PDF 256. Werner, M.H., Huth, J.R., Gronenborn, A.M. & Clore, G.M. (1995) Molecular basis of human 46X,Y sex reversal revealed from the three-dimensional solution structure of the human SRY-DNA complex. Cell 81, 705-714. pubmed PDF 257. Balagurumoorthy, P., Sakamoto, K., Lewis, M.S., Zambrano, N., Clore, G.M., Gronenborn, A.M., Appella, E. & Harrington, R.E. (1995) Four p53 DNA binding domains bind natural p53 response elements and bend the DNA. Proc. Natl. Acad. Sci. U.S.A. 92, 8591-8585. pubmed PDF 258. Lodi, P.J., Ernst, J.A., Kuszewski, J., Hickman, A.B., Engelman, A., Craigie, R., Clore, G.M. & Gronenborn, A.M. (1995) Solution structure of the DNA binding domain of HIV-1 integrase. Biochemistry 34, 9826-9833. pubmed PDF 259. Makhatadze, G.I., Clore, G.M. & Gronenborn, A.M. (1995) Solvent isotope effect and protein stability. Nature Struct. Biol. 2, 852-855. pubmed PDF 260. Werner, M.H., Bianchi, M.E., Gronenborn, A.M. & Clore, G.M. (1995) NMR spectroscopic analysis of the DNA conformation induced by the human testis determining factor SRY. Biochemistry 34, 11998-12004. pubmed PDF 261. Strzelecka, T.E., Clore, G.M. & Gronenborn, A.M. (1995) The solution structure of the Mu Ner protein reveals a helix-turn-helix DNA recognition motif. Structure 3, 1087-1095. pubmed PDF 262. Gronenborn, A.M. & Clore, G.M. (1995) Structures of protein complexes by multidimensional heteronuclear magnetic resonance spectroscopy. CRC Crit. Rev. Biochem. Mol. Biol. 30, 351-385. pubmed 263. Werner, M.H., Clore, G.M., Fisher, C.L., Fisher, R.J., Trinh, L., Shiloach, J. & Gronenborn, A.M. (1995) The solution structure of the human ETS1/DNA complex reveals a novel mode of binding and true sidechain intercalation. Cell 83, 761-771. Erratum: Cell 87, issue No. 2 (1996). PDF Correction of the NMR structure of the ETS1/DNA complex. J. Biomol. NMR 10, 317-328 (1997). pubmed PDF 264. Frank, M.K., Clore, G.M. & Gronenborn, A.M. (1995) Structural and dynamic characterization of the urea denatured state of the immunoglobulin binding domain of Streptococcal protein G. Protein Science 4, 2605-2615. pubmed PDF
265. Clubb, R.T., Mizuuchi, M., Huth, J.R., Omichinski, J.G., Savilahti, H., Mizuuchi, K., Clore, G.M. & Gronenborn, A.M. (1996) The wing of the enhancer binding domain of Mu phase transposase is flexible and essential for efficient transposition. Proc. Natl. Acad. Sci. U.S.A. 93, 1146-1150. pubmed PDF 266. Qin, J., Clore, G.M. & Gronenborn, A.M. (1996) Ionization equilibria for the side chain carboxyl groups in oxidized and reduced human thioredoxin and in the complex with its target peptide from the transcription factor NFkB. Biochemistry 35, 7-13. pubmed PDF 267. Gronenborn, A.M. & Clore, G.M. (1996) Rapid screening for structural integrity of expressed proteins by heteronuclear NMR spectroscopy. Protein Science 5, 174-177. pubmed PDF 268. Pedone, P.V., Ghirlando, R., Clore, G.M., Gronenborn, A.M., Felsenfeld, G. & Omichinski, J.G. (1996) The single Cys2-His2 zinc finger domain of the GAGA protein flanked by basic residues is sufficient for high affinity DNA binding. Proc. Natl. Acad. Sci. U.S.A. 93, 2822-2826. pubmed PDF 269. Werner, M.H., Gronenborn, A.M. & Clore, G.M. (1996) Intercalation, DNA kinking and the control of transcription. Science 271, 778-784. pubmed PDF 270. Grzesiek, S., Bax, A., Clore, G.M., Gronenborn, A.M., Hu, J.-H., Kaufman, J., Palmer, I., Stahl, S.J. & Wingfield, P.T. (1996) The solution structure of HIV-1 Nef reveals an unexpected fold and permits delineation of the binding surface for the SH3 domain of Hck tyrosine protein kinase. Nature Struct. Biol. 3, 340-345. pubmed PDF 271. Clore, G.M., Werner, M.H., Huth, J.R. & Gronenborn, A.M. (1996) Understanding 46X,Y sex reversal at the atomic level. In Biological Structure and Dynamics, (eds. Sarma, R.H. & Sarma, M.H.), Vol. 1, pp. 35-40, Adenine press, New York. In Mechanisms in Transcription, Nucleic Acids and Molecular Biology, (ed., Ecsktein, F. & Lilley, D.M.J.), vol. 11, pp. 265-273, Springer-Verlag, Berlin. 272. Trainor, C.D., Omichinski, J.G., Vandergon, T.L., Gronenborn, A.M., Clore, G.M. & Felsenfeld, G. (1996) A palyndromic regulatory site with vertebrate GATA-1 promoters requires both zinc fingers of the GATA-1 DNA binding domain for high affinity interaction. Mol. Cell. Biol. 16, 2238-2247. pubmed PDF 273. Qin, J., Clore, G.M., Kennedy W.P., Kuszewski, J. & Gronenborn, A.M. (1996) The solution structure of human thioredoxin complexed with its target from Ref-1 reveals peptide chain reversal. Structure 4, 613-620. pubmed PDF 274. Kuszewski, J., Gronenborn, A.M. & Clore, G.M. (1996) Improving the quality of NMR and crystallographic protein structures by means of a conformational database potential derived from structure databases. Protein Science 5, 1067-1080. pubmed PDF 275. Werner, M.H., Huth, J.R., Gronenborn, A.M. & Clore, G.M. (1996) Molecular determinants of mammalian sex. Trends in Biochem. 21, 302-308. pubmed PDF 276. Kuszewski, J., Gronenborn, A.M. & Clore, G.M. (1996) A potential involving multiple proton chemical shift restraints for non-stereospecifically assigned methyl and methylene protons. J. Magn. Reson. Series B 112, 79-81. pubmed PDF 277. Gronenborn, A.M., Frank, M.K. & Clore, G.M. (1996) Core mutants of the immunoglobulin binding domain of Streptococcal protein G: stability and structural integrity. FEBS Lett. 398, 312-316. pubmed PDF 278. Miller, M., Lubkowski, J., Rao, M.J.K., Danishefsky, A.T., Omichinski, J.G., Sakaguchi, K., Sakamoto, H., Appella, E., Gronenborn, A.M. & Clore, G.M. (1996) The oligomerization domain of p53: crystal structure of the trigonal form. FEBS Lett. 399, 166-170. pubmed PDF
279. Clore, G.M. & Gronenborn, A.M. (1997) Dissecting intrinsic chaperonin activity. Proc. Natl. Acad. Sci. U.S.A. 94, 7-8. pubmed PDF 280. Omichinski, J.G., Pedone, P.V., Felsenfeld, G., Gronenborn, A.M. & Clore, G.M. (1997) The solution structure of a specific GAGA factor/DNA complex reveals a modular binding mode. Nature Struct. Biol. 4, 122-132. pubmed PDF 281. Garrett, D.S., Seok, Y.J., Liao, D.I., Peterkofsky, A., Gronenborn, A.M. & Clore, G.M. (1997) Solution structure of the 30 kDa N-terminal domain of Enzyme I of the Escherichia coli phosphoenolpyruvate:sugar phosphotransferase system by multidimensional NMR. Biochemistry 36, 2517-2530. pubmed PDF 282. Kuszewski, J., Gronenborn, A.M. & Clore, G.M. (1997) Improvements and extensions in the conformational database potential for the refinement of NMR and X-ray structures of proteins and nucleic acids. J. Magn. Reson. 125, 171-177. pubmed PDF 283. Pedone, P.V., Omichinski, J.G., Nony, P., Trainor, C., Gronenborn, A.M., Clore, G.M. & Felsenfeld, G. (1997) The N-terminal fingers of cGATA-2 and cGATA-3 are independent sequence-specific DNA binding domains. EMBO J. 16, 2874-2882. pubmed PDF 284. Garrett, D.S., Seok, Y.J., Peterkofsky, A., Clore, G.M. & Gronenborn, A.M. (1997) Identification by NMR of the binding surface for the histidine-containing phosphocarrier protein HPr on the N-terminal domain of enzyme I of the Escherichia coli phosphotransferase system. Biochemistry 36, 4393-4398. pubmed PDF 285. Gronenborn, A.M. & Clore, G.M. (1997) Water in and around proteins. The Biochemist 19, issue 3, 18-21. 286. Tjandra, N., Garrett, D.S., Gronenborn, A.M., Bax, A. & Clore, G.M. (1997) Defining long range order in NMR structure determination from the dependence of heteronuclear relaxation times on rotational diffusion anisotropy. Nature Struct. Biol.4, 443-449. pubmed PDF 287. Nagaich, A.K., Zhurkin, V.B., Sakamoto, H., Gorin, A.A., Clore, G.M., Gronenborn, A.M., Appella, E. & Harrington, R.E. (1997) Architectural accomodation in the complex of four p53 DNA binding domain peptides with the p21/Waf1/Cip1 DNA response element. J. Biol. Chem. 272, 14830-14841. pubmed PDF 288. Wingfield, P.T., Stahl, S.J., Kaufman, J., Zlotnick, A., Hyde, C.C., Gronenborn, A.M. & Clore, G.M. (1997) The extracellular domain of immunodeficiency virus gp41 protein: expression in Escherichia coli, purification and crystallization. |