hoisunglab
Laboratory of Chemical Physics
NIDDK
NIH
Publications (- 2015)
(28)  H. S. Chung,* S. Piana-Agostinetti,* D. E. Shaw, and W. A. Eaton, “Structural origin of slow diffusion in protein folding,” Science 
       Research Article 349 1504 (2015). (*equally contributed)

(27)  K. Truex, H. S. Chung, J. M. Louis, and W A. Eaton, “Testing landscape theory for biomolecular processes with single molecule 
       fluorescence spectroscopy,” Phys. Rev. Lett. 115 018101 (2015).

(26)  H. S. Chung and I. V. Gopich, “Fast single-molecule FRET spectroscopy: theory and experiment,” PCCP Perspective article 16
       18644 (2014).

(25)  H. S. Chung and W. A. Eaton, “Single molecule fluorescence probes dynamics of barrier crossing,” Nature 502 685 (2013).
       News & Views: B. Schuler and J. Clarke, “Rough passage across a barrier,” Nature 502 632 (2013).

(24)  H. S. Chung, T. Cellmer, J. M. Louis, and W. A. Eaton, “Measuring ultrafast protein folding rates from photon-by-photon analysis of
       single molecule fluorescence trajectories,” Chem Phys 422 229 (2013).
       Part of “A tribute to Dr. Robin Hochstrasser”

(23)  E. Boura, B. Rózycki, H. S. Chung, D. Z. Herrick, B. Canagarajah, P. I. Hanson, D. S. Cafiso, W. A. Eaton, G. Hummer, and J. H.
       Hurley, “Solution structure and mechanism of the ESCRT-I and -II membrane budding assembly,” Structure 20 874 (2012).

(22)  H. S. Chung, K. McHale, J. M. Louis, and W. A. Eaton, “Single molecule fluorescence experiments determine protein folding
       transition path times,” Science 335 981 (2012).

(21)  E. Boura, B. Rózycki, D. Z. Herrick, H. S. Chung, J. Vecer, W. A. Eaton, D. S. Cafiso, G. Hummer, and J. H. Hurley, “Solution
       structure of the ESCRT-I complex by small angle x-ray scattering, EPR, and FRET spectroscopy,” Proc Natl Acad Sci USA 108
       9437 (2011).

(20)  H. S. Chung, I. V. Gopich, K. McHale, T. Cellmer, J. M. Louis, and W. A. Eaton, “Extracting rate coefficients from single-molecule
       photon trajectories and FRET efficiency histograms for a fast-folding protein,” J Phys Chem A 115 3642 (2011).
       Part of the “Graham R. Fleming Festschrift”

(19)  H. S. Chung, J. M. Louis, and W. A. Eaton, “Distinguishing between protein dynamics and dye photophysics in single molecule
       FRET experiments,” Biophys J 98 696 (2010).

(18)  H. S. Chung, J. M. Louis, and W. A. Eaton, “Experimental determination of upper bound for transition path times in protein folding
       from single molecule photon-by-photon trajectories,” Proc Natl Acad Sci USA Feature Article 106 11837 (2009).
       Commentary: E. Shakhnovich, “Protein folding roller coaster, one molecule at a time,” Proc Natl Acad Sci USA 106 11823 (2009).

(17)  H. S. Chung, A. T. Shandiz, T. R. Sosnick, and A. Tokmakoff, “Probing the folding transition state of ubiquitin mutants by
       temperature-jump-induced downhill unfolding,”Biochemistry 47 13870 (2008).

(16)  H. S. Chung, and A. Tokmakoff, “Temperature-dependent downhill unfolding of ubiquitin. II. Modeling the free energy surface,”
       Proteins: Structure, Function, and Bioinformatics 72 488 (2008).

(15)  H. S. Chung, and A. Tokmakoff, “Temperature-dependent downhill unfolding of ubiquitin. I. Nanosecond-to-millisecond resolved
       nonlinear infrared spectroscopy,” Proteins: Structure, Function, and Bioinformatics 72 474 (2008).

(14)  Z. Ganim, H. S. Chung, A. W. Smith, L. P. DeFlores, K. C. Jones, and A. Tokmakoff, “Amide I two-dimensional infrared
       spectroscopy of proteins,” Acc Chem Res 41 432 (2008).

(13)  H. S. Chung,* Z. Ganim,* K. C. Jones, and A. Tokmakoff, “Transient 2D IR spectroscopy of ubiquitin unfolding dynamics,”
      Proc Natl Acad Sci USA 104 14237 (2007). (*contributed equally)

(12)  H. S. Chung, M. Khalil, A. W. Smith, and A. Tokmakoff, “A transient 2D IR spectrometer for probing nanosecond temperature-jump
       kinetics,” Rev Sci Instrum 78 063101 (2007).

(11)  A. W. Smith, H. S. Chung, Z. Ganim, and A. Tokmakoff, “Multidimensional IR spectroscopy of site-specific hairpin folding,” in
       Ultrafast Phenomena XV, edited by R. J. D. Miller, A. M. Weiner, P. Corkum, and D. M. Jonas, Springer, New York, 2007.

(10)  L. P. DeFlores, Z. Ganim, S. F. Ackley, H. S. Chung, and A. Tokmakoff, “The anharmonic vibrational potential and relaxation
       pathways of the amide I and II modes of N-methylacetamide,” J Phys Chem B 110 18973 (2006).

(9)  H. S. Chung and A. Tokmakoff, “Visualization and characterization of the infrared active amide I vibrations of proteins,”
      J Phys Chem B 110 2888 (2006).

(8)  A. W. Smith, H. S. Chung, Z. Ganim, and A. Tokmakoff, “Residual native structure in a thermally denatured beta-hairpin,”
     J Phys Chem B 109 17025 (2005).

(7)  H. S. Chung, M. Khalil, A. W. Smith, Z. Ganim, and A. Tokmakoff, “Thermal denaturing of proteins: Equilibrium and transient
      studies using nonlinear infrared probes,” in Ultrafast Phenomena XIV, edited by Takayoshi Kobayashi, Tadashi Okada, Tetsuro
      Kobayashi, Keith A. Nelson, and Sandro De Silvestri, Springer-Verlag, Berlin, 2005, p. 551.

(6)  H. S. Chung, M. Khalil, A. W. Smith, Z. Ganim, and A. Tokmakoff, “Conformational changes during the nanosecond-to-millisecond
      unfolding of ubiquitin,” Proc Natl Acad Sci USA 102 612 (2005).

(5)  H. S. Chung, M. Khalil, and A. Tokmakoff, “Nonlinear infrared spectroscopy of protein conformational change during thermal
      unfolding,” J Phys Chem B 108 15332 (2004).

(4)  N. Demirdöven, C. M. Cheatum, H. S. Chung, M. Khalil, J. Knoester, and A. Tokmakoff, “Two-Dimensional Infrared Spectroscopy of
      Antiparallel beta-Sheet Secondary Structure,” J Am Chem Soc 126 7981 (2004).

(3)  B. S. Zhao, S. H. Lee, H. S. Chung, S. Hwang, W. K. Kang, B. Friedrich, and D. S. Chung, “Separation of a Benzene and Nitric
      Oxide Mixture by a Molecule Prism,”J Chem Phys 119 8905 (2003).

(2)  H. S. Chung, B. S. Zhao, S. H. Lee, K. Cho, S. Hwang, S. H. Shim, S. M. Lim, W. K. Kang, and D. S. Chung, “Molecular Lens
      Applied to Benzene and Carbon Disulfide Molecular Beams,” J Chem Phys 114 8293 (2001).

(1)  B. S. Zhao, H. S. Chung, K. Cho, S. H. Lee, S. Hwang, J. Yu, Y. H. Ahn, J. Y. Sohn, D. S. Kim, W. K. Kang, and D. S. Chung,
      “Molecular Lens of the Nonresonant Dipole Force,” Phys Rev Lett 85 2705 (2000).